Family of structurally-related cell-surface receptors that signal through an intrinsic protein-tyrosine kinase.
Sinónimos
Examples for "erbb receptors "
Examples for "erbb receptors "
1 Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
2 Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
3 Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
4 Distributions of ErbB receptors on membranes of SKBR3 breast cancer cells were mapped by immunoelectron microscopy.
5 ErbB receptors not only function in cancer, but are also key developmental regulators in the nervous system.
1 Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
2 Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
3 Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
4 We describe a new approach that directs ErbB receptor interactions, resulting in biased signaling and phenotypes.
5 Activation of ErbB receptor and downstream signaling molecules were observed in neurites only after heregulin stimulation.
1 There was also a negative correlation between c - erbB - 2 expression and tumor stage.
2 Conversely, inactivation of the ErbB receptors reduces the expression levels of Survivin.
3 This study revealed that erbB - 3 expression was associated with better prognosis.
4 Several recent evidences suggest that NRG1 and their ErbB receptors are involved in ALS.
5 The only cases showing c - erbB - 2 amplification were the two CAexPA cases with high-level immunoreactivity.
6 Drug-related interstitial pneumonitis or cardiac dysfunction associated with other ErbB - targeted therapies was not reported.
7 These ErbB - 2 isoforms function in the nucleus as transcription factors.
8 Importantly, we demonstrate that ERBB family mutant cancers are sensitive to treatment with PI3K inhibitors.
9 We review here the current understanding of ErbB signaling and DNA double strand break repair.
10 Therefore, our results do not support a role for ErbB receptors as auto-antigens in iMG patients.
11 Specifically targeting NRG1 - ErbB signalling may therefore provide a new therapeutic intervention for relieving incision-induced mechanical allodynia.
12 We describe a new approach that directs ErbB receptor interactions, resulting in biased signaling and phenotypes.
13 In addition, differential polymerase chain reaction was used to evaluate c - erbB - 2 gene amplification in these tumors.
14 Activation of ErbB receptor and downstream signaling molecules were observed in neurites only after heregulin stimulation.
15 Distributions of ErbB receptors on membranes of SKBR3 breast cancer cells were mapped by immunoelectron microscopy.
16 However, further knowledge is still needed to clarify the role of the NRG1 - ErbB pathway on MN survival.
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